Supplementary material for published work
Physiologically-Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal Extraction
- M. Gertz, J.B. Houston and A. Galetin
- DMD Fast Forward (doi:10.1124/dmd.111.039248) 01 June 2011
Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from in vitro Clearance and Permeability Data
- M. Gertz, A. Harrison, J.B. Houston & A. Galetin
IC50 Based Approaches as an Alternative Method for Assessment of Time-Dependent Inhibition of CYP3A4
- H.J. Burt, A. Galetin & J.B. Houston
Relative Importance of Intestinal and Hepatic Glucuronidation - Impact on the Prediction of Drug Clearance
- H.E. Cubitt, J.B. Houston & A. Galetin
Grapefruit Juice-Drug Interaction Studies as a Method to Assess the Extent of Intestinal Availability: Utility and Limitations
- M. Gertz, J.D. Davis, A. Harrison, J.B. Houston & A. Galetin
- Curr. Drug Metab., September 2008
Prediction of Drug Clearance by Glucuronidation from in vitro Data: Use of Combined P450 and UGT Cofactors in Alamethicin Activated Human Liver Microsomes
- P.J. Kilford, R. Stringer, B. Sohal, J.B. Houston & A. Galetin
- Drug Metab. Dispos. DMD/2008/023853
A Physiological Model for the Prediction of Intestinal Drug Absorption
- R. Badhan, J. Penny, A. Galetin & J.B. Houston
Reliability of Human Cryopreserved Hepatocytes and Liver Microsomes as in vitro Systems to Predict Metabolic Clearance, Cited in Thesis
- R.A. Stringer, P. Nicklin & J.B. Houston
References for in vivo Clearance Values Cited in Thesis
- M. Griffin
- PhD Thesis: Use of in vitro Metabolism Models for in vivo Drug Metabolic Clearance Prediction
Evaluation of Cryopreserved Human Hepatocytes as an Alternative in vitro System to Microsomes for the Prediction of Metabolic Clearance
- H. Brown, M. Griffin & J.B. Houston
- Drug Metab. Dispos. 35 293-301 2007