Dr Francesco Cellesi PhD, MRSC
Lecturer in Pharmaceutical Biomaterials
- Email: f.cellesi@manchester.ac.uk
- Telephone: +44 (0)161 275 1802
Memberships of Committees and Professional Bodies
Member of the Royal Society of Chemistry
Research
Francesco is currently focusing his research interests on the molecular design and processing of polymeric materials for biomedical applications. Studies currently underway include:
- hydrogels as biocompatible materials, which can be formed at the site of application from soluble precursors (in situ gelation). They possibly contain or deliver biologically active substances and they may be degraded either by cell (enzymatic) activity or by aspecific chemical reactions (hydrolysis, oxidation).
- Colloids, such as nanoparticles, vesicles (liposomes) and micelles, which are able to circulate in body fluids and to respond to environmental factors (temperature, oxidation potential, pH) for obtaining a responsive release of bioactive components.
More information on the web site of the Laboratory of Polymers and Biomaterials
Methodological Knowledge
Biography
Francesco Cellesi is Lecturer in Pharmaceutical Biomaterials in the School of Pharmacy and Pharmaceutical Sciences since September 2006. He joined the University of Manchester in 2003 as PostDoctoral Research associate, and then as Research Fellow in 2006. He completed his PhD studies at the ETH Zurich, Department of Materials, Institute of Biomedical Engineering (2000-2003), after he graduated in Chemical Engineering at the University of Pisa, Italy, in October 1999.
Qualifications
2003 - PhD in Materials Engineering, ETH Zurich (Switzerland)
1999 - Master in Chemical Engineering, University of Pisa (Italy)
Collaborators and affiliated staff
Selected publications
2009
- Liu R, De Leonardis P, Cellesi F, Tirelli N, Saunders BR. (2009). Temperature-Triggered Gelation of Aqueous Laponite Dispersions Containing a Cationic Poly(N-isopropyl acrylamide) Graft Copolymer. Langmuir, 25, 1, 490-496. eScholarID:1d17629 | DOI:10.1021/la802941h
- R. Liu, Cellesi F, Tirelli N, B.R. Saunders. (2009). A study of thermoassociative gelation of aqueous cationic poly(N-isopropyl acrylamide) graft copolymer solutions. Polymer, 50, 6, 1456-1462. eScholarID:1d18896 | DOI:10.1016/j.polymer.2009.01.035
2008
- Kotsokechagia T, Cellesi F, Thomas A, Niederberger M, Tirelli N. (2008). Preparation of ligand-free TiO2 (anatase) nanoparticles through a nonaqueous process and their surface functionalization. Langmuir, 24, 13, eScholarID:1d17628 | DOI:10.1021/la800470e
- Liu R, De Leonardis P, Cellesi F, Tirelli N, Saunders B.R. (2008). Cationic temperature-responsive poly(N-isopropyl acrylamide) graft copolymers: from triggered association to gelation. Langmuir, 24(14), 7099-7106. eScholarID:1d18239 | DOI:10.1021/la8002756
2006
- Cellesi F, Tirelli N. (2006). Sol-gel synthesis at neutral pH in W/O microemulsion: A mehod for enzyme nanoencapsulation in silica gel nanoparticles. Colloids and Surfaces A, 288, 52 - 61. eScholarID:1d13598
- TaglientiA, Cellesi F, CrescenziV, SequiP, ValentiniM, Tirelli N. (2006). Investigating the Interactions of Hyaluronan Derivatives with Biomolecules. The Use of Diffusional NMR Techniques. Macromolecular Bioscience, 6, 611 - 622. eScholarID:1d13582 | DOI:10.1002/mabi.200600041
2005
- Cellesi F, Tirelli N. (2005). A new process for cell microencapsulation and other biomaterial applications: Thermal gelation and chemical cross-linking in 'tandem'. Journal of Material Science: Material in Medicine, 16, 559 - 565. eScholarID:1d11651 | DOI:10.1007/s10856-005-0532-1
2004
- Cellesi F, Tirelli N, Hubbell J.A. (2004). Towards a fully-synthetic substitute of alginate:development of a new process using thermal gelation and chemical cross-linking. Biomaterials, 25, 5115 - 5124. eScholarID:1d7865 | DOI:10.1016/j.biomaterials.2003.12.015
- Cellesi F, WeberW, Fussenegger M, HubbellJ.A, Tirelli N. (2004). Towards a Fully Synthetic Substitute of Alginate: Optimization of a Thermal Gelation/Chemical Cross-Linking Scheme ("Tandem" Gelation) for the Production of Beads and Liquid-Core Capsules. Biotechnology & Bioengineering, 88, 740 - 749. eScholarID:1d9006 | DOI:10.1002/bit.20264
2002
- Cellesi F, Tirelli N, Hubbell. (2002). Materials for Cell Encapsulation via a New Tandem Approach Combining Reverse Thermal Gelation and Covalent Crosslinking. Macromolecular Chemistry and Physics, 203, 1466 - 1472. eScholarID:1d8340 | DOI:10.1002/1521-3935(200207)203:10/11<1466::AID-MACP1466>3.0.CO;2-P