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AMBER parameter database

The parameters archived here are for use with the AMBER force field and may be freely downloaded. For convenience, the parameter sets are divided into:

• cofactors
• carbohydrates
• proteins
• lipids (and equilibrated boxes)
  
• nucleic acids
• organic molecules
• ions
• solvent boxes

Each parameter set is defined by an OFF or PREP file, a FRCMOD or FRCFLD file and information about the parameters, provided under the name of the contributor, which includes:

• information about the developers
• a reference to an article where the parameters have been derived and applied 
• additional comments about the parameters e.g. how they were created, what they were used for and known limitations

When using the parameter set, please be sure to cite the given reference. Standard parameters for proteins and nucleic acids are available elsewhere. Finally, please note that we cannot accept responsibility for the parameter quality archived here.

Please consider contributing your AMBER parameters to this database for other AMBER users to download and use, and to provide a starting point for parametrization of similar molecules. Guidelines are available for AMBER parameter development (AMBER9 Manual, "Specifying a force field", or AMBER8 Manual, "Science Background", p.254). A list of links related to AMBER parameters is also maintained.

The database is maintained by Richard Bryce, to whom specific correspondence and queries about this site should be directed to: 
R.A.Bryce@manchester.ac.uk or by writing to The School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.